Structure prediction
ColabFold / AF2, OpenFold, ESMFold. FASTA → PDB with confidence maps and clean, validated outputs.
- Fast turnaround
- pLDDT / PAE artifacts
- High-throughput capable
Upload FASTA · Get structure + QC report · Powered by DGX Spark
ColabFold is free for one. We run your pipeline at scale.
CandleAI provides computational protein modeling for academic labs, biotech startups, and synbio groups: structure prediction, variant analysis, binder/enzyme design, and high-throughput screening — with automation, QC, and GPU hours that underprice AWS. You buy compute + reliability, not medical advice.
ColabFold · OpenFold · ESMFold
RFdiffusion · ProteinMPNN
QC before delivery
Managed protein pipeline
FASTA → MSA → model → QC → report
Labs hate installing CUDA and babysitting GPUs. We provide the stack, the queue, and the quality gate.
Predict
from $5 / protein
Batch
100–10,000 sequences
GPU
50–80% under AWS
Core services
Computational predictions only. Your lab validates experimentally.
Variants & binders
Mutation impact and stability scoring. Binder / enzyme / antibody candidates via RFdiffusion + ProteinMPNN.
- Variant analysis
- Candidate generation
- Labs do wet-lab validation
Screen + lease
100–10,000 sequences for HT screening. Or lease DGX GPU hours at predictable rates under AWS.
- Proteome-scale friendly
- Idle GPU → lease
- Compute arbitrage desk
How it works
Fast. Accurate. Affordable. QC before you get the package.
1. Submit
FASTA, mutation lists, or design requests. Accept research-use disclaimer.
2. Compute + QC
MSA → model → structural sanity (pLDDT, PAE, RMSD, chain continuity) → agent report.
3. Deliver
PDB + confidence maps + versioned report. Paid jobs also get human review.
Quality control before money
No paid invoice ships without the QC gate. Pilots may use a labeled subset.
Automated checks
- pLDDT thresholds & distributions
- PAE maps where supported
- RMSD vs known references
- Chain continuity / file integrity
Trust layer
- Agent-written summaries (no clinical claims)
- Human review on paid jobs
- Model / DB / pipeline / timestamp versioning
- Disclaimer on every report
Pricing
Founder-special bands. Raise after three paying customers.
Candle Predict
One structure or binder job.
- $5–$300 per protein
- QC-passed PDB + report
- ≤ 48h after queue
Candle Forge
Your pipeline live on Spark.
- $4,500 founder special
- 30% deposit
- Dashboard + API + QC
Start with a free pilot
We prove quality on your sequences before any invoice.
Candle Pro / GPU
Subscription or leased hours.
- $500–$10k+ / month
- GPU lease 50–80% under AWS
- Batch from $0.50 / sequence
Free pilot
Ideal for academic labs, biotech startups, and synbio groups. We run 5–10 proteins, 1 binder design, and 1 mutation batch — labeled pilot QC — so you can judge speed, cleanliness, and reports.
What you get
- 5–10 structure predictions
- 1 binder / enzyme design run
- 1 mutation analysis batch
- Reports with disclaimer + version stamps
Pilots are free. Conversion to paid only after you see results.
Apply
Security & compliance
Data protection
- AES-256 at rest · TLS 1.3 in transit
- HIPAA-ready (BAA available)
- 90-day retention · right to deletion
Your sequences stay yours
- No PHI without signed BAA
- No training on your data by default
- Audit trail on every job